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Cleavage of protease-activated receptors on an immortalized oral epithelial cell line by Porphyromonas gingivalis gingipains

Porphyromonas gingivalis activates protease-activated receptors (PARs) on oral keratinocytes, resulting in downstream signalling for an innate immune response. Activation depends on P. gingivalis gingipains, but could be confounded by lipopolysaccharide signalling through Toll-like receptors. We the...

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Detalhes bibliográficos
Main Authors: Giacaman, Rodrigo A., Asrani, Anil C., Ross, Karen F., Herzberg, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889418/
https://ncbi.nlm.nih.gov/pubmed/19608609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.029132-0
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