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Inhibition of lysosome degradation on autophagosome formation and responses to GMI, an immunomodulatory protein from Ganoderma microsporum

BACKGROUND AND PURPOSE: Autophagic cell death is considered a self-destructive process that results from large amounts of autophagic flux. In our previous study, GMI, a recombinant fungal immunomodulatory protein cloned from Ganoderma microsporum, induced autophagic cell death in lung cancer cells....

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Autors principals: Hsin, I-Lun, Sheu, Gwo-Tarng, Jan, Ming-Shiou, Sun, Hai-Lun, Wu, Tzu-Chin, Chiu, Ling-Yen, Lue, Ko-Huang, Ko, Jiunn-Liang
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504994/
https://ncbi.nlm.nih.gov/pubmed/22708544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02073.x
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