Pharmacological comparison of novel synthetic fenamate analogues with econazole and 2-APB on the inhibition of TRPM2 channels

BACKGROUND AND PURPOSE: Fenamate analogues, econazole and 2-aminoethoxydiphenyl borate (2-APB) are inhibitors of transient receptor potential melastatin 2 (TRPM2) channels and are used as research tools. However, these compounds have different chemical structures and therapeutic applications. Here w...

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Main Authors: Chen, Gui-Lan, Zeng, Bo, Eastmond, Sarah, Elsenussi, Sandra E, Boa, Andrew N, Xu, Shang-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504990/
https://ncbi.nlm.nih.gov/pubmed/22646516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02058.x
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