Efficacy of adjuvant aromatase inhibitor in hormone receptor-positive postmenopausal breast cancer patients according to the body mass index

BACKGROUND: Increased adiposity may trigger signalling pathways that induce aromatase expression. As aromatase inhibitors exert their effects by blocking the aromatase enzyme, higher body mass index (BMI) can reduce the effect of aromatase inhibitors. Thus, we aimed to investigate retrospectively th...

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Autori principali: Sendur, M A N, Aksoy, S, Zengin, N, Altundag, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504952/
https://ncbi.nlm.nih.gov/pubmed/23099804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.473
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