Efficacy of adjuvant aromatase inhibitor in hormone receptor-positive postmenopausal breast cancer patients according to the body mass index

BACKGROUND: Increased adiposity may trigger signalling pathways that induce aromatase expression. As aromatase inhibitors exert their effects by blocking the aromatase enzyme, higher body mass index (BMI) can reduce the effect of aromatase inhibitors. Thus, we aimed to investigate retrospectively th...

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Main Authors: Sendur, M A N, Aksoy, S, Zengin, N, Altundag, K
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
主題:
Clinical Study
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504952/
https://ncbi.nlm.nih.gov/pubmed/23099804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.473
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