Enhancement of N-methyl-N'-nitro-N-nitrosoguanidine transformation of Syrian hamster cells by a phorbol diester is independent of sister chromatid exchanges and chromosome aberrations.

12-O-Tetradecanoylphorbol 13-acetate (TPA), a known tumor promoter, enhances the morphologic transformation of Syrian hamster embryo cells induced by low transforming concentrations of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) (0.025-0.1 microgram/ml) without potentiation of cell lethality or...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Popescu, N C, Amsbaugh, S C, DiPaolo, J A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6938975/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.12.7282
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