Enhancement of N-methyl-N'-nitro-N-nitrosoguanidine transformation of Syrian hamster cells by a phorbol diester is independent of sister chromatid exchanges and chromosome aberrations.

12-O-Tetradecanoylphorbol 13-acetate (TPA), a known tumor promoter, enhances the morphologic transformation of Syrian hamster embryo cells induced by low transforming concentrations of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) (0.025-0.1 microgram/ml) without potentiation of cell lethality or...

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Autori principali: Popescu, N C, Amsbaugh, S C, DiPaolo, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1980
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC350486/
https://ncbi.nlm.nih.gov/pubmed/6938975
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