Soluble Amyloid Precursor Protein 770 Is Released from Inflamed Endothelial Cells and Activated Platelets: A NOVEL BIOMARKER FOR ACUTE CORONARY SYNDROME

Most Alzheimer disease (AD) patients show deposition of amyloid β (Aβ) peptide in blood vessels as well as the brain parenchyma. We previously found that vascular endothelial cells express amyloid β precursor protein (APP) 770, a different APP isoform from neuronal APP695, and produce Aβ. Since the...

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Detalhes bibliográficos
Main Authors: Kitazume, Shinobu, Yoshihisa, Akiomi, Yamaki, Takayoshi, Oikawa, Masayoshi, Tachida, Yuriko, Ogawa, Kazuko, Imamaki, Rie, Hagiwara, Yoshiaki, Kinoshita, Noriaki, Takeishi, Yasuchika, Furukawa, Katsutoshi, Tomita, Naoki, Arai, Hiroyuki, Iwata, Nobuhisa, Saido, Takaomi, Yamamoto, Naomasa, Taniguchi, Naoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504793/
https://ncbi.nlm.nih.gov/pubmed/23033480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398578
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