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Is There a Role for HTLV-1-Specific CTL in Adult T-Cell Leukemia/Lymphoma?

ATLL is an aggressive malignancy of T cells that affects about 5% of individuals infected with HTLV-1. The precise mechanism of oncogenesis is not known, but there is evidence that two regulatory viral proteins, Tax and HBZ, are involved. A high set point proviral load is associated with development...

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Detalhes bibliográficos
Main Authors: Rowan, Aileen G., Bangham, Charles R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504207/
https://ncbi.nlm.nih.gov/pubmed/23259066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/391953
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