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The glmS Ribozyme Cofactor is a General Acid-Base Catalyst
The glmS ribozyme is the first natural self-cleaving ribozyme known to require a cofactor. The D-glucosamine-6-phosphate (GlcN6P) cofactor has been proposed to serve as a general acid, but its role in the catalytic mechanism has not been established conclusively. We surveyed GlcN6P-like molecules fo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504194/ https://ncbi.nlm.nih.gov/pubmed/23113700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307021f |
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