Compensatory Growth of Congenital Solitary Kidneys in Pigs Reflects Increased Nephron Numbers Rather Than Hypertrophy

BACKGROUND: Patients with unilateral MultiCystic Kidney Dysplasia (MCKD) or unilateral renal agenesis (URA) have a congenital solitary functioning kidney (CSFK) that is compensatory enlarged. The question whether this enlargement is due to increased nephron numbers and/or to nephron hypertrophy is u...

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Auteurs principaux: van Vuuren, Stefan H., Sol, Chalana M., Broekhuizen, Roel, Lilien, Marc R., Oosterveld, Michiel J. S., Nguyen, Tri Q., Goldschmeding, Roel, de Jong, Tom P. V. M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504144/
https://ncbi.nlm.nih.gov/pubmed/23185419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049735
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