Family history of alcohol dependence and antidepressant response to an N-methyl-D-aspartate antagonist in bipolar depression

OBJECTIVES: Both ketamine and ethanol are N-methyl-D-aspartate (NMDA) receptor antagonists. Ketamine has rapid antidepressant properties in major depressive disorder (MDD) as well as bipolar depression. In individuals with MDD, a positive family history of alcohol dependence (FHP) was associated wit...

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Autori principali: Luckenbaugh, David A, Ibrahim, Lobna, Brutsche, Nancy, Franco-Chaves, Jose, Mathews, Daniel, Marquardt, Craig A, Cassarly, Christy, Zarate, Carlos A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504126/
https://ncbi.nlm.nih.gov/pubmed/22978511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bdi.12003
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