Family History of Alcohol Dependence and Initial Antidepressant Response to an NMDA Antagonist

BACKGROUND: A high rate of comorbidity exists between mood disorders and alcohol dependence. Furthermore, both ketamine, a dissociative anesthetic with a recently described rapid-onset antidepressant effect, and ethanol are N-methyl-D-aspartate (NMDA) receptor antagonists. Previous investigations of...

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Detalhes bibliográficos
Main Authors: Phelps, Laura E., Brutsche, Nancy, Moral, Jazmin R., Luckenbaugh, David A., Manji, Husseini K., Zarate, Carlos A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727595/
https://ncbi.nlm.nih.gov/pubmed/18996507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.09.029
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