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A Randomized Trial of a Low Trapping Non-Selective N-methyl-D-aspartate (NMDA) Channel Blocker in Major Depression

BACKGROUND: The high-affinity N-methyl-D-aspartate (NMDA) antagonist ketamine exerts rapid antidepressant effects, but has psychotomimetic properties. AZD6765 is a low-trapping NMDA channel blocker with low rates of associated psychotomimetic effects. This study investigated whether AZD6765 could pr...

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Detalhes bibliográficos
Main Authors: Zarate, Carlos A, Mathews, Daniel, Ibrahim, Lobna, Chaves, Jose Franco, Marquardt, Craig, Ukoh, Immaculata, Jolkovsky, Libby, Brutsche, Nancy E, Smith, Mark A., Luckenbaugh, David A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594049/
https://ncbi.nlm.nih.gov/pubmed/23206319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.10.019
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