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Silent Damage of Noise on Cochlear Afferent Innervation in Guinea Pigs and the Impact on Temporal Processing

Noise-exposure at levels low enough to avoid a permanent threshold shift has been found to cause a massive, delayed degeneration of spiral ganglion neurons (SGNs) in mouse cochleae. Damage to the afferent innervation was initiated by a loss of synaptic ribbons, which is largely irreversible in mice....

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Detalhes bibliográficos
Main Authors: Liu, Lijie, Wang, Hui, Shi, Lijuan, Almuklass, Awad, He, Tingting, Aiken, Steve, Bance, Manohar, Yin, Shankai, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504112/
https://ncbi.nlm.nih.gov/pubmed/23185359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049550
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