Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

A major goal in regenerative medicine is the predictable manipulation of human embryonic stem cells (hESCs) to defined cell fates that faithfully represent their somatic counterparts. Directed differentiation of hESCs into neuronal populations has galvanized much interest into their potential applic...

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Detaylı Bibliyografya
Asıl Yazarlar: Patani, Rickie, Lewis, Patrick A, Trabzuni, Daniah, Puddifoot, Clare A, Wyllie, David J A, Walker, Robert, Smith, Colin, Hardingham, Giles E, Weale, Michael, Hardy, John, Chandran, Siddharthan, Ryten, Mina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2012
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504076/
https://ncbi.nlm.nih.gov/pubmed/22681703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07825.x
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