Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

A major goal in regenerative medicine is the predictable manipulation of human embryonic stem cells (hESCs) to defined cell fates that faithfully represent their somatic counterparts. Directed differentiation of hESCs into neuronal populations has galvanized much interest into their potential applic...

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Detalhes bibliográficos
Main Authors: Patani, Rickie, Lewis, Patrick A, Trabzuni, Daniah, Puddifoot, Clare A, Wyllie, David J A, Walker, Robert, Smith, Colin, Hardingham, Giles E, Weale, Michael, Hardy, John, Chandran, Siddharthan, Ryten, Mina
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504076/
https://ncbi.nlm.nih.gov/pubmed/22681703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07825.x
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