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Identification of Biological Markers of Liver X Receptor (LXR) Activation at the Cell Surface of Human Monocytes

BACKGROUND: Liver X receptor (LXR) α and LXR β (NR1H3 and NR1H2) are oxysterol-activated nuclear receptors involved in the control of major metabolic pathways such as cholesterol homeostasis, lipogenesis, inflammation and innate immunity. Synthetic LXR agonists are currently under development and co...

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Detalhes bibliográficos
Main Authors: Rébé, Cédric, Filomenko, Rodolphe, Raveneau, Magalie, Chevriaux, Angélique, Ishibashi, Minako, Lagrost, Laurent, Junien, Jean Louis, Gambert, Philippe, Masson, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504056/
https://ncbi.nlm.nih.gov/pubmed/23185273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048738
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