IP3 Receptor Type 2 Deficiency Is Associated with a Secretory Defect in the Pancreatic Acinar Cell and an Accumulation of Zymogen Granules

Acute pancreatitis is a painful, life-threatening disorder of the pancreas whose etiology is often multi-factorial. It is of great importance to understand the interplay between factors that predispose patients to develop the disease. One such factor is an excessive elevation in pancreatic acinar ce...

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Main Authors: Orabi, Abrahim I., Luo, Yuhuan, Ahmad, Mahwish U., Shah, Ahsan U., Mannan, Zahir, Wang, Dong, Sarwar, Sheharyar, Muili, Kamaldeen A., Shugrue, Christine, Kolodecik, Thomas R., Singh, Vijay P., Lowe, Mark E., Thrower, Edwin, Chen, Ju, Husain, Sohail Z.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504040/
https://ncbi.nlm.nih.gov/pubmed/23185258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048465
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