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DNA gyrase on the bacterial chromosome: possibility of two levels of action.

In previous studies we have shown that oxolinic acid, a specific inhibitor of the A subunit of DNA gyrase, induces DNA cleavage at 100,000-base-pair intervals on the Escherichia coli chromosome. At subsaturating drug concentrations, cleavage is induced at a fraction of these sites and DNA synthesis...

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Bibliografiska uppgifter
Huvudupphovsmän: Drlica, K, Engle, E C, Manes, S H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1980
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC350394/
https://ncbi.nlm.nih.gov/pubmed/6256766
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