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Role of adenylate cyclase in immunologic release of mediators from rat mast cells: agonist and antagonist effects of purine- and ribose-modified adenosine analogs.

The initial monophasic rise in cyclic AMP beginning 5-15 sec after bridging of rat mast cell IgE-Fc receptors precedes the secretion of granule constituents, thereby implying a causal relationship. Direct evidence for a relationship between IgE-dependent transmembrane activation of adenylate cyclase...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Holgate, S T, Lewis, R A, Austen, K F
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1980
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350377/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6256761/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.11.6800
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