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Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells

BACKGROUND: Increased expression of the pro-fibrotic protein connective tissue growth factor (CTGF) has been detected in injured kidneys and elevated urinary levels of CTGF are discussed as prognostic marker of chronic kidney disease. There is evidence that epithelial cells lining the renal tubular...

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Detalhes bibliográficos
Main Authors: Zuehlke, Jonathan, Ebenau, Astrid, Krueger, Bettina, Goppelt-Struebe, Margarete
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503564/
https://ncbi.nlm.nih.gov/pubmed/22938209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-10-25
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