Synapse-Binding Subpopulations of Aβ Oligomers Sensitive to Peptide Assembly Blockers and scFv Antibodies

[Image: see text] Amyloid β42 self-assembly is complex, with multiple pathways leading to large insoluble fibrils or soluble oligomers. Oligomers are now regarded as most germane to Alzheimer’s pathogenesis. We have investigated the hypothesis that oligomer formation itself occurs through alternativ...

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Bibliografiset tiedot
Päätekijät: Velasco, Pauline T., Heffern, Marie C., Sebollela, Adriano, Popova, Izolda A., Lacor, Pascale N., Lee, Kevin B., Sun, Xiaoxia, Tiano, Benjamin N., Viola, Kirsten L., Eckermann, Amanda L., Meade, Thomas J., Klein, William L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2012
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503444/
https://ncbi.nlm.nih.gov/pubmed/23173076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300122k
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