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Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo
Most animal studies using passive administration of HIV broadly neutralizing monoclonal antibodies (bnMAbs) have associated protection against high-dose mucosal viral challenge with relatively high serum concentrations of antibody. We recently identified several bnMAbs remarkable for their in vitro...
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Main Authors: | , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
National Academy of Sciences
2012
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3503218/ https://ncbi.nlm.nih.gov/pubmed/23100539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214785109 |
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