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Assembly of macromolecular complexes by satisfaction of spatial restraints from electron microscopy images

To obtain a structural model of a macromolecular assembly by single-particle EM, a large number of particle images need to be collected, aligned, clustered, averaged, and finally assembled via reconstruction into a 3D density map. This process is limited by the number and quality of the particle ima...

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Detalles Bibliográficos
Main Authors: Velázquez-Muriel, Javier, Lasker, Keren, Russel, Daniel, Phillips, Jeremy, Webb, Benjamin M., Schneidman-Duhovny, Dina, Sali, Andrej
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503186/
https://ncbi.nlm.nih.gov/pubmed/23112201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216549109
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