Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication.
We have inserted a 311-base pair DNA fragment containing the simian virus 40 (SV40) origin of DNA replication, the early promoter, and the tumor (T) antigen binding sites into a bacterial plasmid and cloned it. This recombinant plasmid, pSV01, binds to a purified T antigen in vitro and replicates in...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1980
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350311/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6256739/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.11.6491 |
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