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Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication.

We have inserted a 311-base pair DNA fragment containing the simian virus 40 (SV40) origin of DNA replication, the early promoter, and the tumor (T) antigen binding sites into a bacterial plasmid and cloned it. This recombinant plasmid, pSV01, binds to a purified T antigen in vitro and replicates in...

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Autors principals: Myers, R M, Tjian, R
Format: Artigo
Idioma:Inglês
Publicat: 1980
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC350311/
https://ncbi.nlm.nih.gov/pubmed/6256739
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