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Pseudotyped Influenza A Virus as a Vaccine for the Induction of Heterotypic Immunity

There is a need for vaccines that can protect broadly across all influenza A strains. We have produced a pseudotyped influenza virus based on suppression of the A/PR/8/34 hemagglutinin signal sequence (S-FLU) that can infect cells and express the viral core proteins and neuraminidase but cannot repl...

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Detalhes bibliográficos
Main Authors: Powell, Timothy J., Silk, Jonathan D., Sharps, Jane, Fodor, Ervin, Townsend, Alain R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503098/
https://ncbi.nlm.nih.gov/pubmed/23015719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01820-12
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