Development of Neurological Disease Is Associated with Increased Immune Activation in Simian Immunodeficiency Virus-Infected Macaques

Simian immunodeficiency virus (SIV) infection of macaques can result in central nervous system disorders, such as meningitis and encephalitis. We studied 10 animals inoculated with brain-derived virus from animals with SIV encephalitis. Over half of the macaques developed SIV-induced neurologic dise...

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Autores principales: Dang, Que, Whitted, Sonya, Goeken, Robert M., Brenchley, Jason M., Matsuda, Kenta, Brown, Charles R., Lafont, Bernard A. P., Starost, Matthew F., Iyengar, Ranjini, Plishka, Ronald J., Buckler-White, Alicia, Hirsch, Vanessa M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503031/
https://ncbi.nlm.nih.gov/pubmed/23035225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02174-12
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