Specificity in interaction of benzo[a]pyrene with nuclear macromolecules: implication of derivatives of two dihydrodiols in protein binding.

Benzo[a]pyrene (B[a]P), 7,8-dihydroxy-7,8-dihydro-B[a]P, and 9,10-dihydro-B[a]P are metabolized by hamster embryo cells to derivatives that bind to nuclear macromolecules. The selectivity for different classes of macromolecules varies depending on the compound analyzed. The ratio of DNA specific act...

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Bibliografische gegevens
Hoofdauteurs: MacLeod, M C, Kootstra, A, Mansfield, B K, Slaga, T J, Selkirk, J K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1980
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC350291/
https://ncbi.nlm.nih.gov/pubmed/6935653
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