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Properties of the separated catalytic and regulatory units of brain adenylate cyclase.

Adenylate cyclase from bovine brain cortex was solubilized with 14 mM cholate and 1 M (NH4)2SO4. Gel filtration over a column of Sepharose 6B separated the catalytic unit (CU) from a factor (G/F) that confers responsiveness to 5'-guanylyl imidophosphate (p[NH]ppG) or fluoride. The separated CU,...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Strittmatter, S, Neer, E J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350280/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6935648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.11.6344
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