Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm

Four custom Axiom genotyping arrays were designed for a genome-wide association (GWA) study of 100,000 participants from the Kaiser Permanente Research Program on Genes, Environment and Health. The array optimized for individuals of European race/ethnicity was previously described. Here we detail th...

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Autores principales: Hoffmann, Thomas J., Zhan, Yiping, Kvale, Mark N., Hesselson, Stephanie E., Gollub, Jeremy, Iribarren, Carlos, Lu, Yontao, Mei, Gangwu, Purdy, Matthew M., Quesenberry, Charles, Rowell, Sarah, Shapero, Michael H., Smethurst, David, Somkin, Carol P., Van den Eeden, Stephen K., Walter, Larry, Webster, Teresa, Whitmer, Rachel A., Finn, Andrea, Schaefer, Catherine, Kwok, Pui-Yan, Risch, Neil
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502750/
https://ncbi.nlm.nih.gov/pubmed/21903159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2011.08.007
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