Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm

Four custom Axiom genotyping arrays were designed for a genome-wide association (GWA) study of 100,000 participants from the Kaiser Permanente Research Program on Genes, Environment and Health. The array optimized for individuals of European race/ethnicity was previously described. Here we detail th...

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主要な著者: Hoffmann, Thomas J., Zhan, Yiping, Kvale, Mark N., Hesselson, Stephanie E., Gollub, Jeremy, Iribarren, Carlos, Lu, Yontao, Mei, Gangwu, Purdy, Matthew M., Quesenberry, Charles, Rowell, Sarah, Shapero, Michael H., Smethurst, David, Somkin, Carol P., Van den Eeden, Stephen K., Walter, Larry, Webster, Teresa, Whitmer, Rachel A., Finn, Andrea, Schaefer, Catherine, Kwok, Pui-Yan, Risch, Neil
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502750/
https://ncbi.nlm.nih.gov/pubmed/21903159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2011.08.007
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