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Effect of ligand density, receptor density, and nanoparticle size on cell targeting

It is generally accepted that the presentation of multiple ligands on a nanoparticle surface can improve cell targeting; however, little work has been done to determine whether an optimal ligand density exists. We have recently developed a site-specific bioconjugation strategy that allows for distin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Elias, Drew R., Poloukhtine, Andrei, Popik, Vladimir, Tsourkas, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502720/
https://ncbi.nlm.nih.gov/pubmed/22687896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2012.05.015
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