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Electron Microscopy and 3D Reconstruction Reveals Filamin Ig-Domain Binding to F-Actin
Filamin A (FLNa) is an actin-binding protein that cross-links F-actin into networks of orthogonally branched filaments. FLNa also directs the networks to integrins while responding to mechanochemical signaling pathways. Flexible, 160 nm long FLNa molecules are tail-to-tail dimers, each subunit of wh...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3502691/ https://ncbi.nlm.nih.gov/pubmed/23041423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.09.025 |
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