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Leptin treatment inhibits the progression of atherosclerosis by attenuating hypercholesterolemia in type 1 diabetic Ins2(+/Akita):apoE(-/-) mice

AIMS: The impact of leptin deficiency and its replacement in T1D remain unclear in the context of dyslipidemia and atherosclerosis. The current study has investigated the physiologic role of leptin in lipid metabolism and atherosclerosis in T1D. METHODS AND RESULTS: The present study has employed In...

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Detalhes bibliográficos
Main Authors: Jun, John Y., Ma, Zhexi, Pyla, Rajkumar, Segar, Lakshman
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502687/
https://ncbi.nlm.nih.gov/pubmed/23099119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2012.10.031
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