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Leptin treatment inhibits the progression of atherosclerosis by attenuating hypercholesterolemia in type 1 diabetic Ins2(+/Akita):apoE(-/-) mice

AIMS: The impact of leptin deficiency and its replacement in T1D remain unclear in the context of dyslipidemia and atherosclerosis. The current study has investigated the physiologic role of leptin in lipid metabolism and atherosclerosis in T1D. METHODS AND RESULTS: The present study has employed In...

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書誌詳細
主要な著者: Jun, John Y., Ma, Zhexi, Pyla, Rajkumar, Segar, Lakshman
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502687/
https://ncbi.nlm.nih.gov/pubmed/23099119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2012.10.031
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