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PARP-14 and its enzyme activity regulates Th2 differentiation and allergic airway disease
BACKGROUND: Interleukin-4 (IL-4) and STAT6 play an important role in progression of allergic airway disease (AAD) or asthma. IL-4 and STAT6 mediate T helper 2 (Th2) responses in T cells, and immunoglobulin class switching to IgE in B cells. Both, Th2 responses and IgE promote the asthmatic condition...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3502685/ https://ncbi.nlm.nih.gov/pubmed/22841009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.06.015 |
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