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PARP-14 Functions as a Transcriptional Switch for Stat6-dependent Gene Activation
A subset of poly ADP-ribose polymerases (PARP) that also contain macro domains regulate transcription. One such macro PARP, PARP-14 alters interleukin 4 (IL-4) and Stat6-dependent transcription. Stat6, activated by IL-4 plays an important role in T helper cell immunity and B cell responses. Here we...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023471/ https://ncbi.nlm.nih.gov/pubmed/21081493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.157768 |
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