Effective Deep Brain Stimulation Suppresses Low-Frequency Network Oscillations in the Basal Ganglia by Regularizing Neural Firing Patterns

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for the motor symptoms of Parkinson's disease (PD). The effects of DBS depend strongly on stimulation frequency: high frequencies (>90 Hz) improve motor symptoms, while low frequencies (<50 Hz) are eit...

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Detalhes bibliográficos
Main Authors: McConnell, George C., So, Rosa Q., Hilliard, Justin D., Lopomo, Paola, Grill, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502634/
https://ncbi.nlm.nih.gov/pubmed/23136407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2824-12.2012
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