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Constitutive uncoupling of pathways of gene expression that control growth and differentiation in myeloid leukemia: a model for the origin and progression of malignancy.

Chemical carcinogens and tumor promoters have pleiotropic effects. Tumor initiators can produce a variety of mutations and tumor promotres can regulate a variety of physiological molecles that control growth and differentiation. The appropriate mutation and the regulation of the appropriate molecule...

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Dettagli Bibliografici
Autore principale: Sachs, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1980
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC350232/
https://ncbi.nlm.nih.gov/pubmed/6934543
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