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Constitutive uncoupling of pathways of gene expression that control growth and differentiation in myeloid leukemia: a model for the origin and progression of malignancy.
Chemical carcinogens and tumor promoters have pleiotropic effects. Tumor initiators can produce a variety of mutations and tumor promotres can regulate a variety of physiological molecles that control growth and differentiation. The appropriate mutation and the regulation of the appropriate molecule...
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1980
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC350232/ https://ncbi.nlm.nih.gov/pubmed/6934543 |
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