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Characterization of a variety of neutralizing anti-heparin-binding epidermal growth factor-like growth factor monoclonal antibodies by different immunization methods

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the epidermal growth factor family. The accumulated evidence on the tumor-progressing roles of HB-EGF has suggested that HB-EGF-targeted cancer therapy is expected to be promising. However, the generation of neutraliz...

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Библиографические подробности
Главные авторы: Tsuji, Isamu, Sato, Shuji, Otake, Kentaro, Watanabe, Takahiro, Kamada, Hiroko, Kurokawa, Tomofumi
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502240/
https://ncbi.nlm.nih.gov/pubmed/23007682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.21929
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