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Molecular mechanism of the “feedback loop” model of carcinogenesis

It is commonly accepted that cancer is a genetic disease. The current prevailing theory of carcinogenesis is the somatic mutation theory of carcinogenesis and metastasis (SMT). This theory postulates that mutations in epithelial cells lead to uncontrolled proliferation of tumor cells in a cell-auton...

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Detalhes bibliográficos
Main Authors: Rückert, Felix, Sticht, Carsten, Niedergethmann, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502218/
https://ncbi.nlm.nih.gov/pubmed/23739683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.21177
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