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Molecular mechanisms of nickel carcinogenesis.

Carcinogenic, water-insoluble Ni compounds are phagocytized by cells; and the particles undergo dissolution inside the cell, releasing Ni ions that interact with chromatin. Ni produces highly selective damage to heterochromatin. The longest contiguous region of heterochromatin in the Chinese hamster...

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Bibliografiske detaljer
Main Authors: Costa, M, Salnikow, K, Cosentino, S, Klein, C B, Huang, X, Zhuang, Z
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567374/
https://ncbi.nlm.nih.gov/pubmed/7843086
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