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Molecular mechanisms in nickel carcinogenesis: modeling Ni(II) binding site in histone H4.

Ni(II) compounds are well known as human carcinogens, though the molecular events which are responsible for this are not yet fully understood. It has been proposed that the binding of N(II) ions within the cell nucleus is a crucial element in the mechanism of carcinogenesis. The most abundant protei...

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Bibliographische Detailangaben
Hauptverfasser: Zoroddu, Maria Antonietta, Schinocca, Laura, Kowalik-Jankowska, Teresa, Kozlowski, Henryk, Salnikow, Konstantin, Costa, Max
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1241232/
https://ncbi.nlm.nih.gov/pubmed/12426119
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