Functional Redundancy of SWI/SNF Catalytic Subunits in Maintaining Vascular Endothelial Cells in the Adult Heart

RATIONALE: SWI/SNF chromatin-remodeling complexes utilize either BRG1 or BRM as a catalytic subunit to alter nucleosome position and regulate gene expression. BRG1 is required for vascular endothelial cell (VEC) development and embryonic survival, whereas BRM is dispensable. OBJECTIVE: To circumvent...

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Bibliographische Detailangaben
Hauptverfasser: Willis, Monte S., Homeister, Jonathon W., Rosson, Gary B., Annayev, Yunus, Holley, Darcy, Holly, Stephen P., Madden, Victoria J., Godfrey, Virginia, Parise, Leslie V., Bultman, Scott J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501986/
https://ncbi.nlm.nih.gov/pubmed/22740088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.265587
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