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IRF3 contributes to sepsis pathogenesis in the mouse cecal ligation and puncture model
Much remains to be learned regarding which components of the innate immune response are protective versus detrimental during sepsis. Prior reports demonstrated that TLR9 and MyD88 play key roles in the CLP mouse model of sepsis; however, the role of additional PRRs and their signaling intermediates...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Leukocyte Biology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501894/ https://ncbi.nlm.nih.gov/pubmed/23048204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0312138 |
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