AMP-Activated Protein Kinase α1 Protects Against Diet-Induced Insulin Resistance and Obesity

AMP-activated protein kinase (AMPK) is an essential sensor of cellular energy status. Defects in the α2 catalytic subunit of AMPK (AMPKα1) are associated with metabolic syndrome. The current study investigated the role AMPKα1 in the pathogenesis of obesity and inflammation using male AMPKα1-deficent...

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Autors principals: Zhang, Weiyu, Zhang, Xianling, Wang, Huan, Guo, Xin, Li, Honggui, Wang, Ying, Xu, Xin, Tan, Lyhun, Mashek, Mara T., Zhang, Chunxiang, Chen, Yingjie, Mashek, Douglas G., Foretz, Marc, Zhu, Chuhong, Zhou, Huaijun, Liu, Xu, Viollet, Benoit, Wu, Chaodong, Huo, Yuqing
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2012
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501873/
https://ncbi.nlm.nih.gov/pubmed/22829451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1373
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