Liver X Receptor Modulates Diabetic Retinopathy Outcome in a Mouse Model of Streptozotocin-Induced Diabetes

Endothelial progenitor cells (EPCs), critical for mediating vascular repair, are dysfunctional in a hyperglycemic and/or hypercholesterolemic environment. Their dysfunction contributes to the progression of diabetic macro- and microvascular complications. Activation of “cholesterol-sensing” nuclear...

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Bibliographische Detailangaben
Hauptverfasser: Hazra, Sugata, Rasheed, Adil, Bhatwadekar, Ashay, Wang, Xiaoxin, Shaw, Lynn C., Patel, Monika, Caballero, Sergio, Magomedova, Lilia, Solis, Nathaniel, Yan, Yuanqing, Wang, Weidong, Thinschmidt, Jeffrey S., Verma, Amrisha, Li, Qiuhong, Levi, Moshe, Cummins, Carolyn L., Grant, Maria B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2012
Schlagworte:
Complications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501845/
https://ncbi.nlm.nih.gov/pubmed/22891211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1596
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